Vaginal flora imbalance – Vaginal swab.

Despite having regular sexual intercourse for at least twelve months, 8 to 12% of couples of reproductive age experience fertility problems. Hormonal, vascular, or immune disorders do not explain all of these conception failures. A disturbance (dysbiosis) of the vaginal flora is already correlated with multiple gynecological conditions as well as various issues related to pregnancy and difficulties with medically assisted reproduction. The dysbiosis observed in these patients is characterized by a diverse and abundant vaginal microbiota, with an increased presence of bacteria associated with various intimate infections (bacterial vaginosis, vaginitis, cystitis) and, at the same time, a relative decrease in lactobacilli.”

According to the data analyzed, the conception rate exceeded 72% when lactobacilli accounted for more than 90% of the vaginal microbiota, whereas it dropped to 34% when they were absent. The composition of the vaginal microbiota, particularly a deficiency in lactobacilli, appears to play a crucial role in repeated conception failures.